科研情况
1、Hedgehog/Gli1信号通路调控STMN1表达在胃癌EMT转化和侵袭转移过程中的作用及机制研究,国家自然科学基金课题,第二完成人。
2、胃癌预警早诊、疗效和预后判断标志物的临床验证,重大慢性非传染性疾病防控研究项目消化道肿瘤诊疗生物标志物验证及应用研究,第四完成人。
3、RNF180启动子CpG岛甲基化调控胃癌淋巴结转移机制研究,天津市应用基础与前沿技术研究计划一般项目,第四完成人。
获奖情况
1、“胃癌淋巴结转移分期更新对患者预后评估的意义”获2015年中国抗癌协会科技进步三等奖,第四完成人。
2、“淋巴结转移分期的改良方式对胃癌患者根治术后预后评估的临床研究”获2012年天津市科技进步三等奖,第四完成人。
论文著作
1.张李,潘源,梁寒等,全胃切除术后两种消化道重建术式的前瞻性临床研究阶段报告。中华胃肠外科杂志,2013(12),32-36.
2.张李,蔡明志,邓靖宇等,胃肠间质瘤156例临床分析。中华胃肠外科杂志,2014(17),36-39.
3.张李,梁寒等,ADAMTS9在肿瘤中的研究进展。世界最新医学信息文摘 20(78):36-38.
4.Gang Ma, Yi Sun, Feng lin Cai, Mengmeng zhang, Han Liang,Jingyu Deng,Rupeng Zhang,Li Zhang. Exp Cell Res.2023;427(1).
5.Li Zhang, Han Liang. Comparison of laparoscopic and open resection for gastric gastrointestinal stromal tumors. Cancer and Surgery,2020,1(1):8-17.ISCI
6. Liu JY, Deng JY, Zhang NN, Liu HF, Sun WL, He WT, Zhang L, Liang H. Clinical significance of the skip lymph node metastasis in pN1 stage gastric cancer patients after curative surgery. Gastroenterol Rep 2019;7(3)193-198.(IF=2.96)
7.Hou Y, Deng J, Zhang L, Xie X, Guo X, Sun C, Zhang R, Liang H. Lower expression of PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1) association with poor prognosis of gastric cancer. Int J Clin Exp Med 2015;8(11):20481-20489. (IF=0.166)
8.Deng J, Zhang R, Wu LL, Zhang L, Wang X, Liu Y, Hao X, Liang H. Superiority of the ratio between negative and positive lymph nodes for predicting the prognosis for patients with gastric cancer. Ann Surg Oncol 2015;22(4):1258-1266. ( IF=4.061)
9. Deng J, Cui J, Jiang N, Zhang R, Zhang L, Hao X, LiangH. STAT3 regulation the expression of VEGF-D in HGC-27 gastric cancer cell. Am J Transl Res 2014;6(6):756-767. (IF=3.375)
10.Deng J, Zhang R, Zhang L, Liu Y, Hao X, Liang H. Negative Node Count Improvement Prognostic Prediction of the Seventh Edition of the TNM Classification for Gastric Cancer. PLoS One 2013;8(11):e80082. (IF=2.74)
11.Deng J, Liang H, Zhang R, Sun D, Pan Y, Liu Y, Zhang L, Hao X. STAT3 is associated with lymph node metastasis in gastric cancer. Tumor Biol 2013;34(5):2791-2800.
12.Deng J, Liang H, Zhang R, Sun D, Pan Y, Zhang L, Hao X. Clinicopathologic characteristics and outcomes of surgery of middle-third gastric cancer. Tumour Biol 2012;33(6):2091-2098.
13. Deng J, Liang H, Zhang R, Sun D, Pan Y, Zhang L, Hao X. Clinicopathologic characteristics and outcomes of surgery of middle-third gastric cancer. Tumour Biol 2012;33(6):2091-2098. |